I am coughing up blood – Do I have cancer?

There have been two research studies done, looking at thousand of people to work out how many people with a certain symptom are likely to have cancer. If you are couching up blood, then you should make an appointment and mention this to your GP. The chances are it’s not cancer, but you need [...]

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Does excercise help ease fatigue in people with cancer?

Many people with cancer have fatigue.  Fatigue is tiredness that doesn’t get better when you rest. Fatigue is a very difficult thing to study, it may be caused by having cancer (e.g. the cancer itself might disrupt your normal biological process and that makes you feel fatigued) or it may also be caused by [...]

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Turning p53 on and off

I have written about p53 before and I am sure I will write about it again!  We all have p53 inside us.  We all have a p53 gene and this p53 gene makes p53 protein.  Normally your p53 levels are low but if your DNA gets damaged your p53 increases, damaged cells can be [...]

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New Treatments – PARP Inhibitors

What new cancer treatments are scientists working on? Scientists are testing a new drug for treating some types of cancer called “PARP inhibitors”.  PARP, doesn’t sound very scientific does it?  PARP stands for Poly-ADP ribose phosphorylase  (you can see a picture of it here). PARP is a protein, we all have it inside our [...]

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Antioxidants and Cancer

First of all an apology to those of you using a feed reader, I’ve noticed that my RSS feed has an XML parse error again.  I’m not sure what is causing this, it’s an intermittent fault (the worst kind as they are the hardest to reproduce)  but I am going to redesign my website [...]

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Laboratory Scientists – Cool Links for Researchers

This is a bit of a geeky post, if you are a research scientist here are some links that could make your life easier. Most of them are free (or have a free “basic” version). I haven’t used any of them (yet), but they all look worth a try.

Mendeley – an iTunes for [...]

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Diabetes Drugs and Breast Cancer – What is the connection?

This week I wrote a post on diabetes and breast cancer (September 16th 2009), where I mentioned that the diabetes drug metformin, also known as Glucopahge or Fortamet has been shown to block tumor growth and prolong remission in mice.

I thought I’d write a bit more about this research, it interests me for [...]

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Diabetes and Breast Cancer

Women with diabetes have a slightly higher risk of developing breast cancer than women without diabetes. Most of the studies have looked at people with type 2 diabetes, simply because more people have type 2 diabetes than type 1.  Type 2 diabetes tends to develop as you get older and your are more likely [...]

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Pancreatic Cancer – Alternative diet does NOT make you live longer

Last  month I wrote a short post about pancreatic cancer, where I refered you to a longer post on the Cancer Research UK website.  The post was called “Pancreatic Cancer – Why is it so difficult to treat” I am going to do the same thing again and recommend you read another blog post [...]

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Two years away from a breast cancer cure?

No. Sorry. A lot of papers have been reporting work by Dr Justin Stebbing at Imperial College, London. He works on microRNAs and thinks that cures based on this research are possible in the next couple of years.  I don’t agree. MicroRNAs are fascinating but there are very, very few drugs aimed at them. [...]

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How many people in the UK have had cancer?

In June 2009, the British Journal of Cancer published research looking at the numbers of people, in the UK who had survived cancer. The article is called “Cancer prevalence in the United Kingdom – estimates for 2008”

Why is it an estimate if 2008 has passed? Well, we don’t know which people who have [...]

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The Scientific Method – If we can’t trust science…

If we can’t trust science what can we trust?

This is a geeky post about how scientists do science. Science means many things to many people, but this post applies to virtually all branches of science, be that cancer research or global warning.

Science is a way of checking things out to see if [...]

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Update to the AML Cancer Genome

In November 2008 I wrote about an American laboratory that had sequenced the entire genome of a person with  Acute Myeloid Leukemia (AML).  A genome is the full DNA sequence of an individual, it includes your genes (you have about 30, 000 different genes) and lots of other stuff called “non-coding DNA”. Off all [...]

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Science, methylation and leukaemia

This is a “science” post.  I haven’t written about methylation (meth-EE-lay-shun) before. Why?  Because it’s complicated. It’s hard to understand and it’s even harder to explain. Why am I writing about it now?  Well, there was an interesting study published today showing how early changes in methylation could lead to the development of leukaemia [...]

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Migraines, Estrogens and Breast Cancer. How are they connected?

There was a recent science study that showed people with medically diagnosed migraines are less likely to have breast cancer. The NHS knowledge Service have written a good description of the study and what it does and doesn’t show. You can find it in their “Behind the Headlines” section. They also have a link [...]

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