Seroxat, Tamoxifen and Breast Cancer

The bmj have just published a study that showing that tamoxifen may not prevent breast cancer if women also take the antidepressant Seroxat (paroxetine). This only applies to the Seroxat, other antidepressants did not have this effect. It seems that Seroxat reduces or completely stops the benefit of tamoxifen. The full (technical) article is here,  [...]

Nuclear Pore Proteins and Cancer

I read an interesting article today about nuclear pore proteins The image on the left, is a cell, the nucleus is the blue dot on the right hand side of the green cell. Nuclear pore proteins control what gets in and out of that blue dot.  Researchers have discovered that some of these proteins can [...]

Scottish Chromatin Group – Meeting and Webcast

This one is for the scientists, the Scottish Chromatin group are having a meeting next Wednesday (the 10th of February 2010).  The meeting is being held at the University of Edinburgh from 2pm-6pm, so obviously if you are in (0r near) Edinburgh you can just go along. Interestingly they are also webcasting the meeting, so [...]

Watch a video showing a neutrophil destroying a germ

Everybody has white blood cells inside them, these white blood cells help us fight off infection and keep us healthy. In a drop of blood about this size • you have roughly 6,000 neutrophils.  Neutrophils are a type of white blood cell. For more information on this topic  see my post “What is a normal [...]

Studying lots of proteins at once

I read an interesting paper in Nature Methods this week called “Systems analysis of EGF receptor signalling dynamics with microwestern arrays“.  EGF stand for Epidermal Growth Factor, the EGF receptor is a small protein that “knows” when EGF is present.  Growth Factors generally make cells grow and so if your growth factors are faulty you [...]

Vitamin D and Colorectal Cancer

A Cancer Research UK press release out today suggests that people with higher levels of vitamin D in their blood have a lower risk of colorectal cancer (you can read the original paper in the British Medical Journal Jenab et al 2010).  This is particularly important in Scotland because we only get about 5 % [...]

Microscopes using mobile phone cameras

Not really a cancer post, but certainly an interesting idea.  Researchers in America are developing a new way of using the camera on a mobile phone,  to take pictures of microscope slides when you don’t have access to a full blown laboratory.  This sort of thing will probably be of most use in the developing [...]

Cell Journal – 60 Day Free Trial

This is a geeky post aimed at the scientists, the journal “Cell” is trying out a new way of showing scientific articles online and (in my opinion), it looks great. Normally you have to pay a lot of money to read Cell (an online only individual subscription for one year costs about £180). For [...]

Can a CT scan give you cancer?

Can a CT scan give you cancer?  Yes, occasionally. A research study published on the 14th of December 2009  looked at whether CT scans increase your risk of cancer, this was covered in the Press and Journal “CT scans may increase risk of cancer“.  CT scans (also known as CAT scans) use X-rays (a form [...]

VEGF – How can we stop the blood supply to cancer cells?

I haven’t written about VEGF before, not because it’s not important, it is, in fact VEGF has been shown to be important in a whole range of solid (i.e. lump forming) tumours, these include:

Bladder
Breast
Cervical
Colorectal (bowel)
Esophageal (food pipe)
Glioblastoma multiforme (brain tumour)
Head and neck cancer
Lung cancer
Ovarian cancer
Pancreatic cancer
Renal cell carcinoma

Generally speaking, if you have a lot of [...]